Taking the urban development strategic planning of Zibo city (2017-2030) as an example, this paper analyses the climate suitability assessment of the urban industrial layout based on multivariate data analysis. The wind environment, thermal environment and atmospheric environment, closely related to urban planning, are comprehensively analysed using meteorological, remote sensing and environmental data. The results show that there is a certain spatial difference in the dominant wind direction and wind speed within the planning area. The dominant wind path in Huantai and Linzi, located in the northern part of Zibo, is mostly east-west, and the rest of the area is mainly south-north. The eastern area of Linzi and the central area of Zichuan are regions with high annual wind speeds, while most of Zhoucun, Zhangdian and the southern area of Boshan are regions with small wind speeds. The extent of the urban heat island has expanded significantly over time, with the twoaxis area as the core, showing a sprawling development. The area of the relatively strong and stronger heat island in the planning area has grown from 405 km² in 2009 to 918 km² in 2016, among which Zhangdian displays the fastest growth rate. The results of the sensitivity simulation experiment show that pollution convergence zones are likely to occur in front of the mountain, and the area with a high concentration of PM_2.5 is mainly distributed in the north-central plains of Zibo. The pollution diffusion condition in the northern and eastern regions of the city is relatively good. The diffusion characteristics of air pollutants emitted by industries in various regions are mainly affected by the dominant winds in different areas. Among them, the diffusion of pollutants in the north of Zichuan and the south of Zhangdian is easy to have a greater impact on the entire central city. Comprehensively considering the above analysis results of wind environment, thermal environment, and atmospheric environment, the classification of the sensitive areas of atmospheric environment in the planning area is carried out, and the suitability of the industrial layout for five types of areas is clarified. From the perspective of improving the local climate and atmospheric environment, this paper put forward planning suggestions that provide scientific support for rational allocation of land functions and industrial layout optimisation.